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The course of delirium in acute stroke
Author(s)John McManus, Rohan Pathansali, Hardi Hassan
Journal titleAge and Ageing, vol 38, no 4, July 2009
Pagespp 385-389
Sourcehttp://www.ageing.oxfordjournals.org
KeywordsConfusion ; Stroke ; Admission [hospitals] ; Correlation ; London.
AnnotationSeveral studies have assessed delirium post-stroke, but conflicting results have been obtained. In this study, all consecutive stroke patients admitted to the Stroke Unit at King's College Hospital, London over a 7-month period were assessed for delirium on admission and for 4 consecutive weeks, using the Confusion Assessment Method (CAM). Risk factors for delirium were recorded. Of 100 eligible patients, 82 were recruited over 7 months. Delirium was detected in 23 patients; 21 of these were delirious on their first assessment. 69% of patients who had four weekly assessments were delirious at 4 weeks. Multivariate logistic regression was performed and two models were identified. With unsafe swallow in the analysis, delirium was associated with an unsafe swallow on admission and poor vision pre-stroke. With unsafe swallow removed from the analysis, delirium was associated with an admission C-reactive protein (CRP) >5mg/l and poor vision pre-stroke. Delirious patients had a higher mortality (30.4% vs 1.7%), longer length of stay (62.2 vs 28.9 days), and increased risk of institutionalisation (43.7% vs 5.2%). Delirium is common post-stroke. Most cases develop at stroke onset and remain delirious for an appreciable period. Delirium onset is associated with stroke severity (low admission Barthel), unsafe swallow on admission, poor vision pre-stroke, and raised admission CRP. Delirium is a marker of poor prognosis.
Accession NumberCPA-090728209 A
ClassmarkEDC: CQA: LD:QKH: 49: 82L

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