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Centre for Policy on Ageing | |
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| Effect of parental age at birth on the accumulation of deficits, frailty and survival in older adults | | Author(s) | Ruth E Hubbard, Melissa K Andrew, Kenneth Rockwood |
| Journal title | Age and Ageing, vol 38, no 4, July 2009 |
| Pages | pp 380-384 |
| Source | http://www.ageing.oxfordjournals.org |
| Keywords | Parents ; Children [offspring] ; Longevity ; Life span ; Chronic illness ; Correlation ; Canada. |
| Annotation | Parental age after conception may affect life expectancy. Adult daughters of older fathers appear to live shorter lives and, in this study, being born to a mother aged <25 was an important predictor of exceptional longevity. The effect of parental age on fitness or frailty is unknown. The authors aimed to investigate the relationships between parental age and frailty and longevity in older adults. In the Canadian Study of Health and Aging (CSHA), data were collected on individuals aged 65+ using a Self Assessed Risk Factor Questionnaire and screening interview. In this secondary analysis, 5122 participants had complete data for parental age, frailty status and 10-year survival. Parental age was divided into three groups with cut-offs at 25 and 45 for fathers and 25 and 40 for mothers. Frailty was defined by an index of deficits. Survival was analysed using Kaplan Meter curves and Cox regression with analyses adjusted for subject's age, sex and age of the other parent. Mean maternal age at subject's birth was 29.2 years (standard deviation, SD 6.8) and mean paternal age 33.3 years (SD 7.8). There was no effect of maternal or paternal age on survival for either sons or daughters. Similarly, there was no association between parental age and subject frailty in old age. Thus, the authors did not identify an association between parental age and frailty or longevity in CSHA participants. (RH). |
| Accession Number | CPA-090728208 A |
| Classmark | SR: SS: BGA: BG6: CI: 49: 7S |
Data © Centre for Policy on Ageing |
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| ...from the Ageinfo database published by Centre for Policy on Ageing. |
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