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Antipsychotics increase mortality in elderly patients with dementia
Corporate AuthorNational Prescribing Centre - NPC, NHS
Journal titleMeReC Extra Issue, no 39, May 2009
PublisherNational Prescribing Centre - NPC, Liverpool, May 2009
Pages2 pp
SourceThe National Prescribing Centre, The Infirmary, 70 Pembroke Place, Liverpool L69 3GF. http://www.npc.co.uk
KeywordsDrugs ; Dementia ; Death ; Clinical surveys.
AnnotationThis Extra Issue describes the extended follow-up of the DART-AD trial which found that patients with Alzheimer's disease (AD) who continued antipsychotic medication for behavioural or psychiatric problems were more likely to die than those switched to placebo. DART-AD was a 12 month randomised controlled trial in 165 patients with Alzheimer's disease. Patients were randomised to either continue their antipsychotic medication or to stop treatment and receive placebo instead. It is noted that the National Institute for Health and Clinical Excellence (NICE) has updated its clinical guidelines on the management of schizophrenia, and does not recommend use of any particular drug or group of drugs. (KJ/RH).
Accession NumberCPA-090623204 P
ClassmarkLLD: EA: CW: 3G *

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