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Centre for Policy on Ageing | |
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Depression and excess mortality
— evidence for a dose response relation in community living elderly | | Author(s) | R A Schoevers, M I Geerlings, D J H Deeg |
| Journal title | International Journal of Geriatric Psychiatry, vol 24, no 2, February 2009 |
| Pages | pp 169-176 |
| Source | http://www.interscience.wiley.com/journal/gps |
| Keywords | Depression ; Death ; Living in the community ; Correlation ; Longitudinal surveys ; Netherlands. |
| Annotation | Depression is associated with an increased mortality risk, but the extent of the association of depression characteristics (such as severity and length of exposure to depression) with excess mortality is not known. This study uses data for a randomly selected cohort of 3746 non-demented community-living people aged 65+ from two waves (1990/1991) of the Amsterdam Study of the Elderly (AMSTEL) with a 10-year follow-up of vital status. At baseline, depression was present in 455 subjects; and of the 229 participating at follow-up, 95 (41.5% had remitted and 134 (56.5%) were still depressed. Incident depression was present in 302 subjects (14.4% of those participating in both waves). 1844 subjects died during the study period (49.2%); and both moderate and severe depression predicted 10-year mortality after multivariate adjustment. Chronic depression was associated with a 41% higher mortality risk in 6-year follow-up compared to subjects without depression. In combination with other findings, a causal relationship between depression and mortality is suggested, and may have implications for both preventive and treatment strategies of late-life depression. (RH). |
| Accession Number | CPA-090421209 A |
| Classmark | ENR: CW: K4: 49: 3J: 76H |
Data © Centre for Policy on Ageing |
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| ...from the Ageinfo database published by Centre for Policy on Ageing. |
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