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Combined effect of health behaviours and risk of first ever stroke in 20040 men and women over 11 years' follow-up in Norfolk cohort of European Prospective Investigation of Cancer (EPIC Norfolk)
 — prospective population study
Author(s)Phyo K Myint, Robert N Luben, Nicholas J Wareham
Journal titleBritish Medical Journal, vol 338, no 7695, 14 March 2009
Pagespp 639-642
Sourcewww.bmj.com
KeywordsStroke ; Tobacco smoking ; Diet ; Alcoholic beverages ; Exercise ; Correlation ; Longitudinal surveys ; Norfolk.
Annotation20040 men and women aged 40-79 living in the general community in Norfolk and having no known stroke or myocardial infarction at baseline in 1993-1997 were followed up to 2007. Participants scored one point for each health behaviour: current non-smoking, physically not inactive, moderate alcohol intake (1-14 units a week), and plasma concentration of vitamin C (50 pmol/l or more) indicating fruit and vegetable intake of at least five servings a day, for a total score ranging from 0-4. There were 599 incident strokes over 229993 person years of follow-up (average follow-up 11.5 years). After adjustment for age, sex, body mass index (BMI), systolic blood pressure, cholesterol concentration, history of diabetes and aspirin use, and social class, compared with people with the four health behaviours, the relative risks for stroke for men and women were 1.15 for three health behaviours, 1.58 for two, 2.18 for one, and 2.31 for none. The relations were consistent in subgroups stratified by sex, age, BMI and social class, and after exclusion of deaths within two years. Four health behaviours combined predict a more than twofold difference in incidence of stroke in men and women. (RH).
Accession NumberCPA-090406218 A
ClassmarkCQA: ETT: CFD: YPP: CEA: 49: 3J: 8N *

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