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Centre for Policy on Ageing | |
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Comorbidity and repeat admission to hospital for adverse drug reactions in older adults
— retrospective cohort study | | Author(s) | Min Zhang, C D'Arcy J Holman, Sylvie D Price |
| Journal title | British Medical Journal, vol 338, no 7687, 17 January 2009 |
| Pages | pp 155-158 |
| Source | www.bmj.com |
| Keywords | Drugs ; At risk ; Admission [hospitals] ; Longitudinal surveys ; Australia. |
| Annotation | 28548 patients aged 60+ with a hospital admission for an adverse drug reaction (ADR) during 1980-2000 were followed for 3 years using the Western Australia data linkage system. 5056 patients (17.7%) had a repeat admission for an ADR. Repeat ADRs were associated with male sex, first admission in 1995-99, length of hospital stay, and Charlson comorbidity index. 60% of comorbidities were recorded and taken into account in analysis. In contrast, advancing age had no effect on repeat ADRs. Comorbid congestive cardiac failure, peripheral vascular disease, chronic pulmonary disease, rheumatological disease, mild liver disease, moderate to severe liver disease, moderate diabetes, diabetes with chronic complications, renal disease, any malignancy including lymphoma and leukaemia, and metastatic solid tumours were strong predictive factors. Comorbidities requiring continuing care predicted reduced likelihood of repeat hospital admissions for ADRs. Comorbidity, but not advancing age, predicts repeat admission for ADRs in older adults, especially those with comorbidities managed in the community. Awareness of these predictors can help clinicians to identify which older people are at greater risk of admission for ADRs and, therefore, who might benefit from closer monitoring. (RH). |
| Accession Number | CPA-090406214 A |
| Classmark | LLD: CA3: LD:QKH: 3J: 7YA * |
Data © Centre for Policy on Ageing |
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| ...from the Ageinfo database published by Centre for Policy on Ageing. |
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