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Late and very-late first-contact schizophrenia and the risk of dementia
 — a nationwide register based study
Author(s)Alex Korner, Ana Garcia Lopez, Lise Lauritzen
Journal titleInternational Journal of Geriatric Psychiatry, vol 24, no 1, January 2009
Pagespp 61-67
Sourcehttp://www.interscience.wiley.com/journal/gps
KeywordsSchizophrenia ; At risk ; Dementia ; Longitudinal surveys ; Denmark.
AnnotationSchizophrenic patients with late and very late first contact with the psychiatric hospital system are at two to three times higher risk of subsequently getting a diagnosis of dementia compared to patients with osteoarthritis and compared to the general population. This is the finding of a study which examined linkage of the psychiatric and the somatic nationwide register of all out- and in-patients with hospital contact in Denmark, by identifying first ever contact 1994 to 2001 with one of the index main diagnoses: late (age 40+) and very late first-contact (age 60+) schizophrenia. First-contact osteoarthritis patients as well as data on the general population were used as controls. 12616 and 7712 individuals were used in the late and very late samples respectively; and follow-up time was between 3 and 4.58 years. The rate ratio of developing dementia in late and very late first contact schizophrenia compared to osteoarthritis patients were 3.57 and 3.15 respectively. Compared to the general population, the RR were 2.36 and 2.21 respectively. (RH).
Accession NumberCPA-090121205 A
ClassmarkELK: CA3: EA: 3J: 76K

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