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Centre for Policy on Ageing | |
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| Education plays a different role in frontotemporal dementia and Alzheimer's disease | | Author(s) | Barbara Borroni, Antonella Alberici, Chiara Agosti |
| Journal title | International Journal of Geriatric Psychiatry, vol 23, no 8, August 2008 |
| Pages | pp 796-800 |
| Source | http://www.interscience.wiley.com |
| Keywords | Dementia ; Educational status [elderly] ; Social characteristics [elderly] ; Correlation ; Italy. |
| Annotation | Low levels of education have been reported to be a risk factor for Alzheimer's disease (AD). This study investigated the role of education, other modifiable and non-modifiable factors of frontotemporal dementia (FTD) as compared to AD, progressive supranuclear palsy (PSP) and corticobasal degeneration syndrome (CBDS) patients. 117 FTD patients, 400 AD, 55 PSP and 55 CBDS from the Centre for Neurodegenerative Diseases and the Centre for Movement Disorders, University of Brescia, Italy entered the study. Demographic and clinical characteristics were recorded carefully. Age, gender, family history for dementia and apolipoprotein E (APOE) genotype were considered as non-modifiable factors; education and comorbidities were included as modifiable variables. Regressive analyses were applied in order to identify differences among groups. FTD differed from AD patients in terms of younger age, positive family history and gender. In regard to APOE genotype, no differences between FTD and AD were found, but FTD showed higher prevalence of epsilon 4 allele compared to both CBDS and FTP patients. When modifiable factors were considered, FTD were higher educated than AD patients. Regression analysis identified younger age, positive family history, and education levels as independently associated variables to FTD diagnosis compared to AD. These results highlight that the contribution of education and non-modifiable factors is likely to be different in FTD and AD. (RH). |
| Accession Number | CPA-080819215 A |
| Classmark | EA: F:V: F: 49: 76V |
Data © Centre for Policy on Ageing |
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| ...from the Ageinfo database published by Centre for Policy on Ageing. |
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