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Centre for Policy on Ageing | |
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Predicting cardiovascular risk in England and Wales
— prospective derivation and validation of QRISK2 | | Author(s) | Julia Hippisley-Cox, Carol Coupland, Yana Vinogradova |
| Journal title | British Medical Journal, vol 336, no 7659, 28 June 2008 |
| Pages | pp 1475-1482 |
| Source | http://www.bmj.com |
| Keywords | Cardiovascular diseases ; At risk ; Evaluation ; England ; Wales. |
| Annotation | The aim was to develop and validate version 2 of the QRISK cardiovascular disease algorithm (QRISK2) to provide accurate estimates of cardiovascular risk to patients from different ethnic groups in England and Wales and to compare its performance with the modified version of Framingham score recommended by the National Institute for Health and Clinical Excellence (NICE). Data used derives from 531 practices in England and Wales contributing to the national QRESEARCH database, comprising a total of 2.3 million patients aged 35-74 with 140000 cardiovascular events. It was found that incorporating ethnicity, deprivation and other clinical conditions into the QRISK2 algorithm for risk of cardiovascular disease improves the accuracy of identification of those at high risk in a nationally representative population. At the 20% threshold, QRISK2 is likely to be a more efficient and equitable tool for treatment decisions in the primary prevention of cardiovascular disease. As the validation was performed in a similar population to the population from which the algorithm was derived, it potentially has a "home advantage". Further validation in other populations is therefore advised. (RH). |
| Accession Number | CPA-080702219 A |
| Classmark | CQ: CA3: 4C: 82: 9 * |
Data © Centre for Policy on Ageing |
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| ...from the Ageinfo database published by Centre for Policy on Ageing. |
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