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Lifestyle and diet-related factors in late-life depression - a 5-year follow-up of elderly European men
 — the FINE study
Author(s)Sinikka Bots, Marja Tijhuis, Simona Giampaoli
Journal titleInternational Journal of Geriatric Psychiatry, vol 23, no 5, May 2008
Pagespp 478-484
Sourcehttp://www.interscience.wiley.com
AnnotationLate-life depression is one of the main health problems in older populations and a key element of healthy ageing. Causal relationships of lifestyle- and diet-related factors in late-life depression are unclear, and have been investigated as part of the FINE (Finland, Italy and the Netherlands) study. Altogether, 526 non-demented European men aged 70-89 at baseline were included in the analyses. The association of lifestyle-related and dietary factors with development of categorically defined depression (> = 48/80 on the Zung Self-rating Depression Scale - ZSDS) was assessed in a 3-year follow-up. 59 of the men (11%) developed depression during follow-up. An independent association with development of depression was found for baseline depressive status, a decline in serum total cholesterol level between study years, physical activity, and moderate alcohol intake, but not dietary factors. This study of a well-documented population of older European men confirms that physical activity and moderate alcohol consumption may protect against depression in the old-old. These results are the first to suggest that a decline in serum cholesterol level may predict development of late-life depression. As the effects of age, medication and incipient cognitive decline could not be entirely ruled out, this finding must be treated with care. (RH).
Accession NumberCPA-080618205 A

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