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Vascular disease and apathy in old age
 — the Leiden 85-Plus Study
Author(s)R C van der Mast, D J Vinkers, M L Stek
Journal titleInternational Journal of Geriatric Psychiatry, vol 23, no 3, March 2008
Pagespp 266-271
Sourcehttp://www.interscience.wiley.com
KeywordsVascular diseases ; Apathy ; Octogenarians ; Longitudinal surveys ; Netherlands.
AnnotationApathy is defined as an important loss of motivation in all domains of daily functioning. There are indications that apathy in older people is associated with vascular disease. This association was assessed as part of the Leiden 85-Plus Study, a population-based study of 500 older Dutch people. Vascular disease was determined at baseline, and symptoms of apathy were assessed annually from ages 85 to 90 using the apathy questions of the 15-item Geriatric Depression Scale (GDS). Diagnostic accuracy of the apathy questions was estimated both at baseline and longitudinally. The apathy items of the GDS showed a sensitivity of 60% and a specificity of 85%. At baseline, 69 subjects with apathy but free from depression had significantly more cardiovascular pathologies compared to 287 without apathy. In the 287 who were free of apathy and depression, increase of apathy but not depression during the follow-up was significantly higher for each cardiovascular pathology at baseline. In community-dwelling older people, those with vascular disease were at higher risk of developing apathy but not depression. This suggests that apathy and depression in old age have different aetiologies. (RH).
Accession NumberCPA-080430201 A
ClassmarkCQP: EPA: BBM: 3J: 76H

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