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Longitudinal body composition changes in old men and women
 — interrelationships with worsening disability
Author(s)Francesco Fantin, Vincenzo Di Francesco, Giorgia Fontana
Journal titleJournals of Gerontology: Series A, Biological Sciences and Medical Sciences, vol 62A, no 12, December 2007
Pagespp 1375-1381
Sourcehttp://www.geron.org
KeywordsOlder men ; Older women ; Weight ; Physical disabilities ; Comparison ; Longitudinal surveys ; Italy.
AnnotationFew studies have evaluated prospectively body composition changes and their relationships with worsening disability as people age. Patients from 11 general practices in Verona, Italy (97 women and 62 men, mean ages 71.4 and 71.6 respectively) underwent dual energy x-ray absorptiometry determinations at baseline and 2- and 5.5-year follow-ups to measure total body and leg fat (FM) and total, appendicular and leg fat-free mass (FFM). Height, weight, body mass index (BMI) and waist circumference (as well as reported disabilities using a four-level scale) were also evaluated at the same time intervals. In both sexes, total FM did not change significantly, while total total, appendicular and leg FM and total, appendicular and leg FFM significantly decreased. In weight-stable men and women, appendicular and leg FM significantly increased and BMI and waist circumference, and total FM significantly increased. Men lost significantly more total, appendicular and leg FFM than did women, irrespective of whether they maintained or lost weight. Over the follow-up period, 43.3% of women and 43.5% of men declined in one or more levels of reported disability. The authors evaluated the effect of age, baseline BMI, FM, FFM, number of diseases, baseline 6-minute walking test, categories of weight change, total, appendicular, or leg FFM changes, total FM and waist changes on the probability of a decline in one or more levels of reported disability score over the follow-up period, taking gender into account. Patients having appendicular and leg FFM were 2.15 and 2.53 times, respectively, more likely to to report increased disability than were patients without FFM loss. (RH).
Accession NumberCPA-080305210 A
ClassmarkBC: BD: 4X6: BN: 48: 3J: 76V

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