Centre for Policy on Ageing
 

 

Survival of parents and siblings of supercentenarians
Author(s)Thomas Perls, Iliana V Kohler, Stacy Andersen
Journal titleJournals of Gerontology: Series A, Biological Sciences and Medical Sciences, vol 62A, no 9, September 2007
Pagespp 1028-1035
Sourcehttp://www.geron.org
KeywordsLongevity ; Siblings ; Parents ; Centenarians ; United States of America.
AnnotationGiven previous evidence of familial predisposition for longevity, it was hypothesised that the siblings and parents of supercentenarians (those aged 110+) were predisposed to survive to very old age, and that relative to their birth cohorts, their relative survival probabilities (RSPs) are even higher than what has been observed for the siblings of centenarians. Mean age at death conditional upon survival to ages 20 and 50 and survival probabilities from ages 20 and 50 to higher ages were determined for 50 male and 56 female siblings and 54 parents of 29 supercentenarians. These estimates were contrasted with comparable estimates based on birth cohort-specific mortality experience for the US and Sweden. Conditional on survival to age 20, mean age at death of supercentenarians' siblings was 81 years for men and women. Compared with respective Swedish and US birth cohorts, these estimates were 17% to 20% (12-14 years) higher for the brothers and 11%-14% (8-10 years) higher for the sisters. Sisters had a 2.9 times greater probability and brothers had a 4.3 greater probability of survival from age 20 to age 90. Mothers of supercentenarians had a 5.8 times greater probability of surviving from age 50 to age 90. Fathers also experienced an increased survival probability from age 50 to age 90 pf 2.7, but it failed to attain statistical significance. The RSPs of siblings and mothers of supercentenarians revealed a substantial survival advantage and were most pronounced at the oldest ages. The RSP to age 90 in siblings of supercentenarians was approximately the same as that reported for siblings of centenarians. It is possible that greater RSPs are observed for reaching even higher ages such as 100 years, but a larger sample of supercentenarians and their siblings and parents is needed to investigate this possibility. (RH).
Accession NumberCPA-080305205 A
ClassmarkBGA: SV: SR: BBT: 7T

Data © Centre for Policy on Ageing

...from the Ageinfo database published by Centre for Policy on Ageing.
 

CPA home >> Ageinfo Database >> Queries to: webmaster@cpa.org.uk