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Quality of life in dementia
 — a 2-year follow-up study
Author(s)Pierre Missotten, Michel Ylieff, David Di Notte
Journal titleInternational Journal of Geriatric Psychiatry, vol 22, no 12, December 2007
Pagespp 1201-1207
Sourcehttp://www.interscience.wiley.com
KeywordsDementia ; Quality of life ; Evaluation ; Longitudinal surveys ; Belgium.
AnnotationA quality of life (QoL) measure, Alzheimer Disease Related Quality of Life (ADRQL) was administered three times to a cohort of 127 subjects in this Belgian 2-year longitudinal study. In addition, several clinical instruments - Mini Mental State Examination (MMSE), IADL, ADL and Clinical Dementia Rating Modified (CDR-M) - were also administered. ADRQL data analysis did not reveal significant modifications of QoL over the 2-year period, whereas results from clinical instruments showed a significant deterioration. On the group, the variations of ADRQL scores were limited with some improvement after the first year, followed by some deterioration after the second year. On the other hand, the ADRQL scores fluctuated every year by at least 10 points for more than half of the subjects. With dementia evolution, it was observed that the clinical variables were more strongly correlated with ADRQL scores and with more significant predictors. This varied from 5.9% (MMSE) in 2002 to 40.01% in 2004 (MMSE and CDR-M). QoL did not develop in a strictly linear manner following the deterioration of clinical state. This suggests that the evolution of QoL is also determined by other variables relating to the physical and social environment of the patients. Their role seems particularly important for the mild to moderate stages of dementia. (RH).
Accession NumberCPA-080212202 A
ClassmarkEA: F:59: 4C: 3J: 76E

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