| |
Centre for Policy on Ageing | |
 | |
|
| Comparison of behavioral and psychological symptoms in early-onset and late-onset Alzheimer's disease | | Author(s) | Yasutaka Toyota, Manabu Ikeda, Shunichiro Shinagawa |
| Journal title | International Journal of Geriatric Psychiatry, vol 22, no 9, September 2007 |
| Pages | pp 896-901 |
| Source | http://www.interscience.wiley.com |
| Keywords | Dementia ; Early ; Late ; Symptoms ; Behaviour disorders ; Personality disorders ; Evaluation ; Comparison ; Japan. |
| Annotation | When comparing early-onset Alzheimer's disease (EO-AD) and late-onset Alzheimer's disease (LO-AD), some symptomatological differences in clinical features can be seen between them. Rapid progression, more severe language problems or visuospatial dysfunction occur more often in EO-AD patients. However, there have been very few reports about the differences in behavioural and psychological symptoms between these two groups. In this Japanese study, 307 consecutive outpatients with AD wre put into an EO-AD group (46 patients) or an LO-AD group (261 patients). In terms of Neuropsychiatric Inventory (NPI) total score, significant differences were found: EO-AD 10.3 ±10.9; LO-AD 17.8 ±17.0, and number of patients who experienced each NPI sub-scale score (delusion, EA-AD 13%; LO-AD 50.6%). There were no differences in cognitive functions or dementia severity between the two groups. In EO-AD, behavioural and psychological symptoms are relatively fewer than LO-AD at the first medical assessment. (RH). |
| Accession Number | CPA-071113213 A |
| Classmark | EA: 4J: 4L: CT: EP: EK: 4C: 48: 7DT |
Data © Centre for Policy on Ageing |
|
| ...from the Ageinfo database published by Centre for Policy on Ageing. |
| |
|