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Genetic and environmental influences on hearing in older women
Author(s)Anne Viljanen, Pertti Era, Jaakko Kaprio
Journal titleJournals of Gerontology: Series A, Biological Sciences and Medical Sciences, vol 62A, no 4, April 2007
Pagespp 447-452
Sourcehttp://www.geron.org
KeywordsOlder women ; Twins ; Hearing Impairment ; Cognitive processes ; Biological ageing ; Evaluation ; Testing ; Finland.
AnnotationAs part of the Finnish Twin Study on Ageing, hearing was measured in 193 monozygotic (MZ) and 114 dizygotic (DZ) female twin pairs aged 63-76. Audiometric measured hearing was tested using standardised methods in soundproof conditions. Self-reported hearing was assessed by a structured question. Quantitative genetic modelling was used for data analysis. No significant difference in age, exposure to noise, hearing aid use, auditory diseases or accidents, or number of self-reported chronic conditions or prescription medicines were observed between MZ and DZ twins. A genetic component in common accounted for 75% of the variance in the better ear's hearing threshold level, and 54% in the better ear's speech recognition threshold level according to a bivariate genetic analysis. In addition, 10% of the variance in the better ear's speech recognition threshold level was explained by its specific genetic component. Individual difference in audiometrically measured air-conducted hearing threshold level (0.5-4kHz) and speech recognition threshold level in the better ear were largely accounted for by genetic differences between individuals. In contrast, self-reported hearing appears to be accounted for solely by environmental factors. (RH).
Accession NumberCPA-070926225 A
ClassmarkBD: SVR: BV: DA: BH: 4C: 3T: 76L

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