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Centre for Policy on Ageing | |
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| Subjectively reported sleep quality and excessive daytime somnolence in Parkinson's disease with and without dementia, dementia with Lewy Bodies and Alzheimer's disease | | Author(s) | Frauke Boddy, Elise N Rowan, Debbie Lett |
| Journal title | International Journal of Geriatric Psychiatry, vol 22, no 6, June 2007 |
| Pages | pp 529-535 |
| Source | http://www.interscience.wiley.com |
| Keywords | Sleep behaviour ; Sleep disorders ; Parkinson's disease ; Dementia ; Evaluation ; North Tyneside ; Sunderland. |
| Annotation | Subjective sleep quality and excessive daytime somnolence (EDS) was compared in controls, Parkinson's disease with (pDD) and without dementia (PD), dementia with Lewy bodies (DLB) and Alzheimer's disease (AD). The researchers investigated whether sleep dysfunction and EDS associate with motor phenotype in PD, PDD and DLB. Patients and controls (research volunteers and spouses of patients) were recruited from dementia and movement disorder clinics in Newcastle and Sunderland. Assessments included the Epworth Sleepiness Scale (ESS) and Pittsburgh Sleep Quality Index (PSQI). EDS was more frequent in PD, DLB and PDD patients than in AD. PDD, PD and DLB patients also had worse sleep quality when compared to AD and controls. Baseline postural instability-gait difficulty (PIDG) motor phenotype in PDD was associated with a higher ESS score and frequency of EDS, but this association was lost at 2 years. PSQI scores did not differ between PIDG dominant and non-dominant PD, PDD and DLB patients. EDS and poor sleep quality are greater in PD, PDD amd DLB compared with AD. The dissociation of EDS and motor phenotype suggests their pathophysiology is anatomically and/or temporally distinct. (RH). |
| Accession Number | CPA-070627226 A |
| Classmark | CG: CTS: CR6: EA: 4C: 86B: 86E |
Data © Centre for Policy on Ageing |
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| ...from the Ageinfo database published by Centre for Policy on Ageing. |
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