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Centre for Policy on Ageing | |
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| Low dose aspirin and cognitive function in the women's health study cognitive cohort | | Author(s) | Jae Hee Kang, Nancy Cook, JoAnn Manson |
| Journal title | British Medical Journal, vol 334 no 7601, 12 May 2007 |
| Pages | pp 987-990 |
| Source | http://www.bmj.com |
| Keywords | Older women ; Drugs ; Mental health [elderly] ; Longitudinal surveys ; United States of America. |
| Annotation | The women's health study was a randomised, placebo controlled trial of low dose aspirin and vitamin E in the prevention of cardiovascular disease and cancer among American women. Participants were 6377 women aged 65+ who took low dose aspirin on alternate days or a placebo for a mean 9.6 years. The women had three cognitive assessments at 2-year intervals by telephone. At the initial assessment (mean 5.6 years after randomisation), cognitive performance in the aspirin group was similar to that of the placebo group. Mean decline in the global score from the first ot the final cognitive assessment was also similar in the aspirin group compared to placebo groups. The risk of substantial decline (in the worth 10th centile of decline) was also comparable between the groups. Findings were similar for verbal memory; however, a 20% lower risk was observed for decline in category fluency with aspirin. Long term use of low dose aspirin does not provide overall benefits for cognition among generally healthy women aged 65+. (RH). |
| Accession Number | CPA-070514226 A |
| Classmark | BD: LLD: D: 3J: 7T * |
Data © Centre for Policy on Ageing |
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| ...from the Ageinfo database published by Centre for Policy on Ageing. |
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