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Centre for Policy on Ageing | |
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| Patient versus informant reported quality of life in the earliest phases of Alzheimer's disease | | Author(s) | Asmus Vogel, Erik Lykke Mortensen, Steen G Hasselbalch |
| Journal title | International Journal of Geriatric Psychiatry, vol 21, no 12, December 2006 |
| Pages | pp 1132-1138 |
| Source | http://www.interscience.wiley.com |
| Keywords | Dementia ; Early ; Informal care ; Quality of life ; Evaluation ; Denmark. |
| Annotation | From a Danish prospective research programme including newly referred patients (aged 60+ and MMSE greater than 20), 40 patients with very early Alzheimer's disease (AD) were included. Quality of life (QoL) was assessed using the QoL-AD and Euro QoL-5 domain (EQ-5D) scales. Anosognosia (patients overestimating their QoL) was rated on a categorical scale by an examiner; MMSE, Geriatric Depression Scale (GDS), Danish Adult Reading Test and Frontal Behavioural Inventory were also administered. On most QoL measures, patients rated their QoL higher than their informants. Anosognosia was not associated with QoL but significantly with an inverse impact on the agreement between patient and informant ratings of QoL. Self-reported QoL was significantly correlated to depression but not to age, dementia severity, behavioural symptoms or memory impairment. Informant ratings of QoL were significantly related to behavioural symptoms; and informant ratings on the EQ-5D Visual Analogue scale were significantly correlated to patient reported depression. That patients with early AD generally reported higher QoL than their informants was associated with the presence of anosognosia. (RH). |
| Accession Number | CPA-070131209 A |
| Classmark | EA: 4J: P6: F:59: 4C: 76K |
Data © Centre for Policy on Ageing |
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| ...from the Ageinfo database published by Centre for Policy on Ageing. |
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