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Centre for Policy on Ageing | |
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| Association of depression with Alzheimer's disease and vascular dementia in an elderly Arab population of Wadi-Ara, Israel | | Author(s) | Abdalla Bowirrat, Marlene Oscar-Berman, Giancarlo Logroscino |
| Journal title | International Journal of Geriatric Psychiatry, vol 21, no 3, March 2006 |
| Pages | pp 246-251 |
| Source | http://www.interscience.wiley.com |
| Keywords | Arab ; Depression ; Dementia ; Correlation ; Israel. |
| Annotation | Because dementia and depression share common risk factors, the authors investigated risk factors for depression in Arab subjects with Alzheimer's disease (AD) and vascular dementia (VaD). Of 823 individuals in this door-to-door, cross-sectional survey of all adults aged 60+ in an Arab community of rural Israel, 168 had dementia of Alzheimer's type (DAT) and 49 had VaD. Vascular risk factors, including the ApoE-e4 allele, were more prevalent among VaD than DAT subjects. Depressive symptoms were present in 57% of DAT patients and 86% of VAD patients. Depressed DAT individuals had a greater history of ischaemic cardiovascular or cerebrovascular disease (CV/CBV) than non-depressed DAT subjects, but depressed DAT subjects were less likely to have the ApoE-e4 allele. Within the VaD group, there were no differences in the distribution of cardiovascular risk factors in individuals with and without depressive symptoms, and ApoE-e4 was more prevalent among those with depressive symptoms. Thus, depressive symptomatology is prevalent among subjects with dementia in this Arab community. Further studies are needed to clarify the role of ApoE in depression onset in different ethnic groups with DAT. (RH). |
| Accession Number | CPA-060928209 A |
| Classmark | TKR: ENR: EA: 49: 7H6 |
Data © Centre for Policy on Ageing |
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| ...from the Ageinfo database published by Centre for Policy on Ageing. |
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