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Differences in heart rate variability between depressed and non-depressed elderly
Author(s)Koen G van der Kooy, Hein P J van Hout, Harm W J van Marwijk
Journal titleInternational Journal of Geriatric Psychiatry, vol 21, no 2, February 2006
Pagespp 147-150
Sourcehttp://www.interscience.wiley.com
KeywordsDepression ; Cardiovascular systems ; Nervous systems ; Correlation ; Netherlands.
AnnotationHeart rate variability (HRV) is a measure of cardiac autonomic functioning. This study was to determine whether older primary care patients with a major depressive disorder (MDD) have lower HRV compared to non-depressed patients. A cross-sectional comparison of 136 older people with MDD and 136 non-depressed controls matched for age and gender were recruited in family practices in the Netherlands. Depression was determined according to the DSM-IV criteria using the Primary Care Evaluation of Mental Disorders (PRIME-MD). HRV was measured with an electrocardiogram (ECG) during a 5-minute supine rest. Multivariate analysis showed statistically significant decrease in HRV in MDD patients compared with controls. Other primary care patients with MDD have a reduced HRV. This may explain why depression is a risk factor for cardiovascular disease and mortality. (RH).
Accession NumberCPA-060928204 A
ClassmarkENR: BKK: BKN: 49: 76H

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