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A systematic review of prevalence and incidence studies of dementia with Lewy bodies
Author(s)Julia Zaccai, Chere McCracken, Carol Brayne
Journal titleAge and Ageing, vol 34, no 6, November 2005
Pagespp 561-566
Sourcehttp://www.ageing.oupjournals.org
KeywordsDementia ; Literature reviews.
AnnotationSubstantial variation in the prevalence of dementia with Lewy bodies (DLB) has been reported with estimates ranging from 0 to 26.3% of all dementia cases, potentially making it the second most common dementia subtype. The aim of this study was to review systematically and critically for the first time previous studies of the clinical prevalence and incidence of DLB in the population. PubMed was used for the literature search. Selected articles had to describe an original study that provided a prevalence and/or incidence number for the whole population for DLB as defined by pre-set clinical criteria and findings. Six studies reporting the prevalence of DLB and one reporting the incidence of DLB met the inclusion criteria. Prevalence estimates, depending on case criteria, range from 0 to 5% with regard to the general population, and from 0 to 30% of all dementia cases. The only estimate for DLB incidence is 0.1% a year for the general population, and 3.2% a year for all dementia cases. The number of available studies was too small to hypothesise on the potential effect of age, sex and genetic background on the results. There is a general consensus that DLB must be considered in the range of neurodegenerative conditions in older people. (RH).
Accession NumberCPA-060202209 A
ClassmarkEA: 64A

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