| |
| |
| |
Centre for Policy on Ageing | |
 | |
|
Neuropsychiatric symptoms of dementia
— cross-sectional analysis from a prospective longitudinal Belgian study | | Author(s) | Sebastian Engelborghs, Karen Maartens, Guy Nagels |
| Journal title | International Journal of Geriatric Psychiatry, vol 20, no 11, November 2005 |
| Pages | pp 1028-1037 |
| Source | http://www.interscience.wiley.com |
| Keywords | Dementia ; Symptoms ; Behaviour disorders ; Cross sectional surveys ; Longitudinal surveys ; Belgium. |
| Annotation | Given the rather limited knowledge on profiles of neuropsychiatric symptoms (behavioural and psychological signs and symptoms of dementia, BPSD) in several degenerative dementias, the authors designed a prospective study for which they present baseline data. Diagnosed according to strictly applied clinical diagnostic criteria, 205 patients with probable Alzheimer's disease (AD), 25 with frontotemporal dementia (FTD), 39 with mixed dementia (MXD) and 23 with dementia with Lewy bodies (DLB) were included. All underwent a neuropsychological examination and behavioural assessments with the Middleheim Frontality Score (MFS), Behave-AD, Cohen Mansfield Agitation Inventory, and Connell Scale for Depression in Dementia. In AD and MXD, activity disturbances and aggressiveness occurred in more than 80% of the patients. With a prevalence of 70%, apathy was very common, whereas delusions and hallucinations were rare in FTD patients. Frequently used behavioural assessment scales like the Behave-AD systematically underestimated BPSD in FTD whereas the MFS displayed high sensitivity for frontal lobe symptoms. Hallucinations discriminated DLB patients from other dementias. A high prevalence of distribution (65%) in DLB pointed to frontal lobe involvement. Behavioural assessment may thus help differentiating between different forms of dementia, further stressing the need for the development of new and more sensitive behavioural assessment scales. (RH). |
| Accession Number | CPA-060106208 A |
| Classmark | EA: CT: EP: 3KB: 3J: 76E |
Data © Centre for Policy on Ageing |
|
| ...from the Ageinfo database published by Centre for Policy on Ageing. |
| |
|
|