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Centre for Policy on Ageing | |
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Counting the calories
— the role of specific nutrients in extension of life span by food restriction | | Author(s) | Matthew D W Piper, William Mair, Linda Partridge |
| Journal title | Journals of Gerontology: Series A, Biological Sciences and Medical Sciences, vol 60A, no 5, May 2005 |
| Pages | pp 549-555 |
| Source | http://www.geron.org |
| Keywords | Diet ; Vitamins ; Longevity ; Life span ; Biological sciences ; Research Reviews. |
| Annotation | Reduction of food intake without malnourishment extends life span in many different organisms. Most of the work in this field has been performed with rodents, showing that both restricting access in the entire diet and restricting individual dietary components can cause life-span extension. Thus, for insights into the mode of action of such interventions, it is of great interest to to investigate the aspects of diet that are critical for life span extension. Further studies on the mechanisms of how food components modify life span are well suited to the model organism Drosophila melanogaster, because of its short life span and ease of handling and containment. The authors summarise practical aspects of implementing dietary restriction in this organism, and also highlight the major advances already made, delineation of the nutritional components that are critical for life-span extension will help to reveal the mechanisms by which it operates. (RH). |
| Accession Number | CPA-051103206 A |
| Classmark | CFD: CFE: BGA: BG6: Y7: 3A:6KC |
Data © Centre for Policy on Ageing |
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| ...from the Ageinfo database published by Centre for Policy on Ageing. |
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