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Diseases and impairments as risk factors for onset of disability in the older population in England and Wales
 — findings from the Medical Research Council Cognitive Function and Ageing Study
Author(s)Nicola A Spiers, Ruth J Matthews, Carol Jagger
Journal titleJournals of Gerontology: Series A, Biological Sciences and Medical Sciences, vol 60A, no 2, February 2005
Pagespp 248-254
Sourcehttp://www.geron.org
KeywordsPhysical disabilities ; Ill health ; Cognitive impairment ; At risk ; Cognitive processes ; Longitudinal surveys.
AnnotationPart of the Medical Research Council Cognitive Function and Ageing Study (MRC-CFAS) reports the association between self-reported diseases and impairments and 2-year onset of disability in a prospective study of people aged 65+ living in urban and rural areas of England and Wales. The authors initially reviewed risk factors for onset of disability in 33 prospective studies of functional decline in older people published 1998 to 2001. In the present study, disability was defined as requiring help from another person at least several times a week, and was assessed by dependency in activities of daily living (ADLs). Among prevalent conditions, arthritis (population attributable risk 11.4%) and cognitive impairment indicated by a Mini Mental State Examination score of 21 or more (population attributable risk 6.8%) were powerful predictors of incident disability. Baseline cognitive impairment, stroke, treated diabetes, chronic airways obstruction, coronary heart disease (CHD) and treated hypertension were significantly associated with both incident disability and mortality, whereas Parkinson's disease, eyesight problems and arthritis were significantly disabling conditions not associated with mortality. Prevalent and incident conditions must be considered as risk factors to accurately assess potential benefits from prevention. (RH).
Accession NumberCPA-051103202 A
ClassmarkBN: CH: E4: CA3: DA: 3J

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