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Effect of multivitamin and multimineral supplements on morbidity from infections in older people (MAVIS trial)
 — pragmatic, randomised, double blind, placebo controlled trial
Author(s)Alison Avenell, Marion K Campbell, Jonathan A Cook
Journal titleBritish Medical Journal, vol 331, no 7512, 6 August 2005
Pagespp 324-327
Sourcehttp://www.bmj.com
KeywordsVitamins ; Diet ; Infectious diseases ; Preventative medicine ; Longitudinal surveys ; Grampian.
AnnotationThe Writing Group of the MAVIS trial at the Health Services Research Unit, University of Aberdeen, sought to examine whether supplementation with multivitamins and multiminerals influences self-reported rates of infection, use of health services and quality of life in people aged 65+. Participants were 910 men and women aged 65+, recruited from six general practices in Grampian, Scotland, who did not take vitamins or minerals. They were randomised to take one tablet daily of a multivitamin and multimineral supplement or a placebo for one year. Supplementation did not significantly affect contacts with primary care and days of infection per year, nor was quality of life affected. No statistically significant findings were found for secondary outcomes (antibiotic prescriptions, hospital admissions, adverse events, or compliance). Thus, routine multivitamin and multimineral supplementation of older people living at home does not affect self-reported infection-related morbidity. (RH).
Accession NumberCPA-050906223 A
ClassmarkCFE: CFD: CJA: LK2: 3J: 9N *

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