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Relationship of exercise and other risk factors to depression of Alzheimer's disease
 — the LASER-AD study
Author(s)Ciaran Regan, Cornelius Katona, Zuzana Walker
Journal titleInternational Journal of Geriatric Psychiatry, vol 20, no 3, March 2005
Pagespp 261-268
Sourcehttp://www.interscience.wiley.com
KeywordsExercise ; Depression ; Dementia ; Longitudinal surveys ; London ; South East England.
AnnotationThis study is part of a larger longitudinal study of people with Alzheimer's disease (AD) and their carers in London and South East Region (the LASER-AD). Information was collected from 224 people with AD and their caregiver using standardised cognitive, psychological and behavioural instruments. Exercise levels were classified in three categories: absent, moderate and rigorous, using the two previous week's exercise to confirm regularity and recency. 9/51 (17.6%) depressed participants took exercise compared with 76/173 (13.9%) non-depressed. Not taking part in other activities (hobbies and interests) was associated with depression less so than lack of exercise. Independent predictors of depression were lack of exercise, using cholinesterase inhibitors, and having less involvement in hobbies or interests. None of the institutional risk factors for depression for older people was associated with depression in AD. Taking regular exercise may protect against depression in AD. (RH).
Accession NumberCPA-050322205 A
ClassmarkCEA: ENR: EA: 3J: 82L: 82Z

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