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A neurologist's view of Alzheimer's disease and dementia
Author(s)Robert Katzman
Journal titleInternational Psychogeriatrics, vol 16, no 3, September 2004
Pagespp 259-274
Sourcehttp://journals.cambridge.org
KeywordsDementia ; At risk ; Literature reviews.
AnnotationDuring the first 60 years of the twentieth century, senile dementia was the concern of psychiatrists, not neurologists. Patients with chronic dementia were cared for in psychiatric hospitals. Even at the turn of the 20th century, when life expectancy was less than 49 years, senile dementia was the third most common admission diagnosis to psychiatric hospitals in New York State. In this article, the author reviews the developing view of Alzheimer's disease (AD) and genetic, age, demographic and education risk factors. The overriding risk factor is age, the prevalence of AD doubling with every five years of age until 90. Low education, head injury and low foliate levels are examples of potentially modifiable risk factors. The concluding section to this article suggests that cognitive and leisure activity may be protective against the development of AD, but any protective functions can only be confirmed by clinical trials. (RH).
Accession NumberCPA-050216203 A
ClassmarkEA: CA3: 64A

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