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The Middelheim Frontality Score
 — a behavioural assessment scale that discriminates frontotemporal dementia from Alzheimer's disease
Author(s)Peter Paul De Deyn, Sebastian Engelborghs, Jos Saerens
Journal titleInternational Journal of Geriatric Psychiatry, vol 20, no 1, January 2005
Pagespp 70-79
Sourcehttp://www.interscience.wiley.com
KeywordsDementia ; Memory disorders ; Behaviour disorders ; Evaluation ; Belgium.
AnnotationDespite neuropsychological and behavioural differences between Alzheimer's disease (AD) and frontotemporal dementia (FTD), clinical diagnostic criteria have failed to discriminate FTD from AD patients. The authors have developed the Middelheim Frontality Score (MFS), a disease-long clinical and behavioural assessment tool that measures frontal lobe features. They set up this prospective study of 400 clinically diagnosed AD and 62 FTD patients, to assess discriminatory power and intra- and inter-rater variability. The MFS was obtained by summating the scores obtained in a standardised fashion on ten items yielding a total maximal score of 10. Information was assessed through an interview of the patient and his/her caregiver, clinical files and behavioural observation. Comparing mean total MFS scores, FTD patients had significantly higher scores than AD patients. Distribution of scores on individual MFS items was significantly different between both disease groups. A moderately positive and highly significant correlation was shown between the total MFS score and diagnostic FTD, which suggests that this scale reliably discriminates between FTD and AD patients. (RH).
Accession NumberCPA-050127215 A
ClassmarkEA: EH: EP: 4C: 76E

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