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Centre for Policy on Ageing | |
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| A longitudinal study of Parkinsonism and disability in a community population of older people | | Author(s) | Anne M Murray, David A Bennett, Carlos F Mendes de Leon |
| Journal title | Journals of Gerontology: Series A, Biological Sciences and Medical Sciences, vol 59A, no 8, August 2004 |
| Pages | pp 864-870 |
| Source | http://www.geron.org |
| Keywords | Parkinson's disease ; Physical disabilities ; Living in the community ; Longitudinal surveys ; United States of America. |
| Annotation | Parkinsonism signs in patients without Parkinson's disease (PD) are often undetected but occur frequently in older people and are often considered benign. The authors conducted a prospective, longitudinal, community-based population study in East Boston, MA, using a stratified random sample of 155 community residents aged 65+. Four categories of Parkinsonism signs were measured at baseline: bradykinesia, gait disturbance, rigidity, and tremor. Parkinsonism was defined as the presence of two or more categories of Parkinsonism signs; cases of PD were excluded from the analyses. Parkinsonism at baseline strongly predicted subsequent disability. On average, a person with Parkinsonism had a disability level at follow-up equal to that of a comparable person approximately 16.7 years for men and 8 years for women. The rate of developing disability of people with Parkinsonism increased each year. Gait impairment and bradykinesia strongly predicted subsequent disability, while tremor and rigidity did not. The effect of Parkinsonism was attenuated but still persistent in people with coexistent moderate-to-severe impairment or stroke. Thus, Parkinsonism predicts progressive disability in the older community population, and has a marked ageing effect on disability level. (RH). |
| Accession Number | CPA-041130231 A |
| Classmark | CR6: BN: K4: 3J: 7T |
Data © Centre for Policy on Ageing |
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| ...from the Ageinfo database published by Centre for Policy on Ageing. |
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