Centre for Policy on Ageing



Predictors of depressive symptoms in persons with Alzheimer's disease
Author(s)	David W Gilley, Robert S Wilson, Julia L Bienias
Journal title	Journals of Gerontology: Series B, Psychological Sciences and Social Sciences, vol 59B, no 2, March 2004
Pages	pp P75-P83
Source	http://www.geron.org
Keywords	Depression ; Symptoms ; Screening ; Dementia ; Correlation ; Longitudinal surveys ; United States of America.
Annotation	In a 4-year longitudinal study, the authors used the 17-item Hamilton Rating Scale for Depression (HRSD) to evaluate factors related to the development of depressive symptoms in 410 Americans with Alzheimer's disease (AD). Structured interviews were conducted with family members. On the basis of informant ratings of premorbid personality, the authors associated neuroticism with a higher rate of depressive symptoms, particularly mood disturbances. They associated greater cognitive impairment with a small reduction in mood symptoms and a modest increase in somatic symptoms. Among demographic variables, somatic symptoms were more common in men and mood symptoms were inversely related to age. Depressive symptoms in AD appear to follow a more predictable pattern of expression than previously described. (RH).
Accession Number	CPA-040705215 A
Classmark	ENR: CT: 3V: EA: 49: 3J: 7T
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...from the Ageinfo database published by Centre for Policy on Ageing.