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Life long changes in cognitive ability are associated with prescribed medications in old age
Author(s)John M Starr, Brian McGurn, Martha Whiteman
Journal titleInternational Journal of Geriatric Psychiatry, vol 19, no 4, April 2004
Pagespp 327-332
Sourcehttp://www.interscience.wiley.com
KeywordsDrugs ; Mental health [elderly] ; Children ; Longevity ; Octogenarians ; Longitudinal surveys ; Scotland.
AnnotationThe Scottish Mental Survey of 1932 (SMS1932) tested the mental ability in 87,498 people born in 1921. Results of the Moray House Test (MHT) for 478 of the survivors aged 80 without dementia were compared with those for 1932, along with Hospital Anxiety and Depression Scale (HADS) score, history of disease, and current prescribed medications. Clinically, the degree to which drugs impair cognition in relatively fit, older people may not be apparent. However, in population terms, medication use, particularly polypharmacy, is important. Statins, used as currently indicated for cardiovascular disease, appear promising in ameliorating cognitive decline in older people. However, firm recommendations of their use should await the outcome of ongoing randomised trials. (RH).
Accession NumberCPA-040505217 A
ClassmarkLLD: D: SBC: BGA: BBM: 3J: 9A

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