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Cognitive decline in high-functioning older adults
 — reserve or ascertainment bias?
Author(s)H Tuokko, D D Garrett, I McDowell
Journal titleAging & Mental Health, vol 7, no 4, July 2003
Pagespp 259-270
Sourcehttp://www.tandfonline.com
KeywordsCognitive impairment ; Dementia ; Educational status [elderly] ; Longitudinal surveys ; Canada.
AnnotationWith data from a prospective, population-based study of incident dementia, the Canadian Study of Health and Aging (CSHA), the authors classified participants as being high- (HF) or low-functioning (LF) in three ways: educational and occupational attainments, and estimated premorbid IQ. They observed that, in accordance with both the BRC and cognitive reserve models, fewer HF older people were diagnosed with dementia after 5 years. Contrary to expectation, no difference on rate of memory deterioration was observed between those HF and LF people who exhibited mild cognitive impairment at CHSA-1. However, HF people who subsequently were diagnosed with dementia (CHSA-2) showed more rapid decline on 5 of the 6 memory measures over time than did LF persons diagnosed with dementia at CHSA-2. When performance on measures of memory functioning at CHSA-1 were examined for highly educated older people, significantly more of those with dementia at CHSA-2 (n=59) had scores falling within or below the average range in comparison to normative standards than those who continued to show no cognitive impairment (n=159). The findings suggest that the lower incidence of dementia for HF people may be primarily the result of ascertainment bias, not underlying differences in brain or cognitive reserve. (RH).
Accession NumberCPA-030806223 A
ClassmarkE4: EA: F:V: 3J: 7S

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