Centre for Policy on Ageing



The role of volumetric MRI in understanding mild cognitive impairment and similar classifications
Author(s)	K J Anstey, J J Maller
Journal title	Aging & Mental Health, vol 7, no 4, July 2003
Pages	pp 238-250
Source	http://www.tandfonline.com
Keywords	Cognitive impairment ; Screening ; Evaluation ; Literature reviews.
Annotation	The authors review 19 empirical studies of mild cognitive impairment (MCI), age-associated memory impairment (AAMI) and related classifications reporting volumetric data obtained through magnetic resonance imaging (MRI) on the hippocampus, entorhinal cortex and amygdala. Their review identifies a wide range of factors that vary between studies, for example the range of definitions and criteria for samples of patients "at risk" of Alzheimer's disease (AD). Longitudinal studies confirm that initial hippocampal volume is predictive of conversion to AD. The authors suggest that greater standardisation in methodology and the development of normative age-referenced databases of regional brain volumes is required. (RH).
Accession Number	CPA-030806221 A
Classmark	E4: 3V: 4C: 64A
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...from the Ageinfo database published by Centre for Policy on Ageing.