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Differential patterns of age-related mortality increase in middle age and old age
Author(s)Shiro Horiuchi, Caleb E Finch, France Meslé
Journal titleJournals of Gerontology: Series A, Biological Sciences and Medical Sciences, vol 58A, no 6, June 2003
Pagespp 495-507
KeywordsDeath rate [statistics] ; Middle aged ; Age groups [elderly] ; Diseases ; Longitudinal surveys ; France.
AnnotationIt is often assumed that ageing is a uniform process throughout adulthood, because of the approximately linear increase of logarithmic mortality. The authors explored this assumption by analysing cause-specific mortality increases in France from 1979 to 1994. Rising rapidly at ages 30-54 years ("middle age") are death rates from malignant neoplasms at various sites, acute myocardial infarction, hypertensive disease, and liver cirrhosis. Steeply increasing at 65-89 years ("old age") are death rates from certain infectious diseases, particularly of the respiratory system, certain types of accidents, non-alcoholic mental disorders (probably due mainly to Alzheimer's disease and senile dementia), heart failure, cerebrovascular disease, and some "vague" categories. The processes at work may be fundamentally different in these two life history stages, such that the mortality rise in middle age reflects specific chronic diseases that develop prematurely in some high-risk individuals, whereas the mortality increase in old age is dominated by senescent processes that eventually raise the vulnerability of almost all individuals to multiple pathologies. (RH).
Accession NumberCPA-030718206 A
ClassmarkS5: SE: BB: CJ: 3J: 765

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