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Effects of educational attainment and occupational status on cognitive and functional decline in persons with Alzheimer-type dementia
Author(s)Thomas Fritsch, McKee J McClendon, Kathleen A Smyth
Journal titleInternational Psychogeriatrics, vol 14, no 4, December 2002
Pagespp 347-364
KeywordsDementia ; Educational status [elderly] ; Economic status [elderly] ; Cognitive impairment ; United States of America.
AnnotationResearchers have suggested that educational attainment and occupational status - indicators of cognitive amd/or neurological "reserve" - can help people compensate for clinical manifestations of Alzheimer's disease (AD), such as the rates of cognitive and functional decline. In the present study, the authors used multilevel analysis for repeated measures to study the effects of educational attainment and occupational status on rates of decline in cognition (Mini Mental State Examination, MMSE) and function (Cleveland Scale for Activities of Daily Living, CSADL). Subjects included those with "probable" or "possible" AD drawn from the Alzheimer's Disease Research Center registry in Cleveland, Ohio - 482 in the analysis of cognitive decline, 450 in the analysis of functional decline. When controlling for year of birth, gender, ethnicity, and duration of illness, an inverse relationship was found between number of years of education and rate of decline to MMSE, but effects of occupational status were not significant. Neither educational attainment nor occupational status affected rate of decline in functional ability. Thus, it could be that the protective effects of reserve may be established early in life, before people enter the workforce. (RH).
Accession NumberCPA-030516202 A
ClassmarkEA: F:V: F:W: E4: 7T

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