Centre for Policy on Ageing



Depression in vascular dementia
Author(s)	Paul Naarding, Inge de Koning, Fop van Kooten
Journal title	International Journal of Geriatric Psychiatry, vol 18, no 4, April 2003
Pages	pp 325-330
Keywords	Stroke ; Depression ; Dementia ; Netherlands.
Annotation	After a stroke, cognitive, affective and behavioural disturbances are common. It has been suggested that the nature of affective symptomatology can help differentiate organic from psychological depression. Cognitive and affective symptoms were assessed in 78 stroke patients recruited from the Rotterdam Stroke Databank (RSD). Principal component analysis revealed three distinct sub-syndromes: one with predominantly mood symptoms, one with essentially psychomotor symptoms, and one with vegetative symptoms. All three symptoms were independently and strongly related to a diagnosis of major depressive disorder according to DSM-III-R criteria. The psychomotor factor was also firmly associated with dementia; and discriminant analysis gave further support to the conclusion that some of the depressive features, in particular the psychomotor factor, are at least partly related to the organic brain damage from stroke. (RH).
Accession Number	CPA-030515209 A
Classmark	CQA: ENR: EA: 76H
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