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A three-factor analytic model of the MADRS in geriatric depression
Author(s)R D Parker, Elizabeth P Flint, Hayden B Bosworth
Journal titleInternational Journal of Geriatric Psychiatry, vol 18, no 1, January 2003
Pagespp 73-77
KeywordsDepression ; Screening ; Evaluation ; United States of America.
AnnotationThe authors examined a sample of 225 geriatric outpatients and inpatients with major depression (MD), participants from the US National Institute for Mental Health (NIMH) Clinical Research Center (MRHCRC) for the Study of Depression in Later Life. Their study examined whether items for the Montgomerie-Asberg (i.e. Montgomery-Asberg) Depression Rating Scale (MADRS) form distinct sub-groups in geriatric depressive patients that might form the basis of new outcome measures for tracking treatment effects. Three distinct interpretable factors were obtained: dysphoric apathy or retardation (comprising apparent sadness, reported sadness, lassitude, reduced concentration, and inability to feel); psychic anxiety (comprising inner tension, pessimistic thoughts, and suicidal thoughts); and vegetative symptoms resulting from items involving appetite and sleep. These three factors may be usable for monitoring focused treatment outcomes. (RH).
Accession NumberCPA-030217009 A
ClassmarkENR: 3V: 4C: 7T

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