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Depressive symptoms and cognitive decline in elderly people
 — longitudinal study
Author(s)Sabrina Paterniti, Marie-Hélène Verdier-Taillefer, Carole Dufouil
Journal titleBritish Journal of Psychiatry, vol 181, November 2002
Pagespp 406-410
KeywordsDepression ; Symptoms ; Cognitive impairment ; Assessment procedures for mental patients ; Longitudinal surveys ; France.
AnnotationA sample 1003 French people aged 59-71 from the Étude sur le Vieillissement Artériel (EVA), with a Mini-Mental State Examination (MMSE) score of 26+ was selected for this study, to test whether depressive symptoms predict cognitive decline in older people with normal cognition. Cognitive decline was defined as a drop of at least 3 points on the MMSE at 4-year follow-up. Baseline high levels of depressive symptoms (as measured by the Center for Epidemiologic Study depression scale - CES-D) predicted a higher risk of cognitive decline at 4-year follow-up. The MMSE score of participants with depression was more likely to fall below 26 at 2-year follow-up, and to remain below 26 at 4-year follow-up than the MMSE score of those without depressive symptoms. Thus, high levels of depressive symptoms, when persistent, are associated with cognitive decline in older people. (RH).
Accession NumberCPA-021202001 A
ClassmarkENR: CT: E4: DA:4C: 3J: 765

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