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Centre for Policy on Ageing | |
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Terminal decline and markers of cerebro- and cardiovascular disease
— findings from a longitudinal study of the oldest old | | Author(s) | Linda B Hassing, Boo Johansson, Stig Berg |
| Journal title | Journals of Gerontology: Series B, Psychological Sciences and Social Sciences, vol 57B, no 3, May 2002 |
| Pages | pp P268-P276 |
| Keywords | Mental ageing ; Cardiovascular diseases ; Cerebrovascular diseases ; Octogenarians ; Twins ; Longitudinal surveys ; Sweden. |
| Annotation | The cognition-survival relationship was examined for 466 non-demented individuals, age range 80-98 at baseline, as part of the Swedish Origins of Variance in the Old-Old (OCTO Twin Study) a longitudinal study. During 6 years of follow-up (at 2-year intervals), 206 had died. Four survival groups were defined on the basis of mortality prior to the subsequent measurement occasion. Tests of cognitive functioning encompassed the domains of crystallised knowledge, including reasoning, visuo-spatial ability, short-term memory, episodic memory, and speed. Significant associations were found between cognitive performance at baseline and subsequent survival. After adjusting for stroke and markers of cardiovascular disease, the authors found that only three out of six cognitive domains remained significant predictors of survival. The longitudinal analysis revealed limited evidence for an accelerated decline prior to daeth. The main results suggested that level of cognitive performance in late life is associated with proximity to death, that this relationship is long-standing, and that it is partially influenced by compromised cardio- and cerebrovascular functioning. (RH). |
| Accession Number | CPA-020617209 A |
| Classmark | D6: CQ: CQ5: BBM: SVR: 3J: 76P |
Data © Centre for Policy on Ageing |
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| ...from the Ageinfo database published by Centre for Policy on Ageing. |
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