Centre for Policy on Ageing



Dementia in people with Down's syndrome
Author(s)	Janette Tyrrell, Mary Cosgrave, Mary McCarron
Journal title	International Journal of Geriatric Psychiatry, vol 16, no 12, December 2001
Pages	pp 1168-1174
Keywords	Cognitive impairment ; Dementia ; Evaluation ; Cross sectional surveys ; Ireland.
Annotation	285 people with Down's syndrome (DS), aged 35-74 were included in this Irish cross-sectional study. Diagnosis of dementia was made using modified DSM-IV criteria. Cognitive tests used were the Down's syndrome Mental Status Examination (DSMSE), Test for Severe Impairment (TSI), and adequate function was measured by Daily Living Skills Questionnaire (DLSQ). Overall prevalence of dementia was 13.3%. Presence of dementia was associated with epilepsy, myoclonus, and head injury. The demented group was significantly older (n=38, mean age 54.7) than the non-demented (n=246, mean age 45.6). The combination of DLSQ score, age, and presence of epilepsy were found to predict presence of dementia in those with DS. (RH).
Accession Number	CPA-020118206 A
Classmark	E4: EA: 4C: 3KB: 763
Data © Centre for Policy on Ageing

...from the Ageinfo database published by Centre for Policy on Ageing.