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Genetic and environmental influences on self-reported reduced hearing in the old and the oldest old
Author(s)Kaare Christensen, Henrik Frederiksen, Howard J Hoffman
Journal titleJournal of the American Geriatrics Society, vol 49, no 11, November 2001
Pagespp 1512-1517
KeywordsHearing Impairment ; Biological ageing ; Twins ; Over 70s ; Evaluation ; Denmark.
AnnotationInterviews conducted in 1995 with 77% of the 3,099 twin individuals aged 75+ from the Danish Twin Registry were contacted again in 1997 and 1999, along with a further 2,778 twins age 70-76 regarding genetic factors in reduced hearing. The authors found that genetic factors play an important role in self-reported reduced hearing in both men and women aged 70+. Because self-reports of reduced hearing involve misclassification, this estimate of the genetic influence on hearing disabilities is probably conservative. Hence, genetic and environmental factors play a substantial role in reduced hearing in the old and oldest-old. This suggests that clinical epidemiological studies of age-related hearing loss should include not only information on environmental exposures, but also on family history of hearing loss, and, if possible, biological samples for future studies of candidate genes for hearing loss. (RH).
Accession NumberCPA-011210219 A
ClassmarkBV: BH: SVR: BBK: 4C: 76K

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