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Depressive symptoms in patients with Alzheimer's disease
Author(s)Nitin Purandare, Alistair Burns, Sarah Craig
Journal titleInternational Journal of Geriatric Psychiatry, vol 16, no 10, October 2001
Pagespp 960-964
KeywordsDepression ; Symptoms ; Dementia.
AnnotationA comparison was made between the depressive symptom profiles of 30 patients with Alzheimer's disease (AD) who did not have co-existing depression and 30 patients with major depression who did not have co-existing dementia. The main objective was to identify symptoms common to both disorders, and those which may be able to differentiate AD from major depression. Depressive symptoms were profiled using the Hamilton Depression Rating Scale (HDRS), the Cornell Scale for Depression in Dementia (CSDD), and the Geriatric Depression Scale (GDS). Depressive symptoms were present in AD in the absence of coexistent major depression. Certain depressive symptoms from all three scales such as sadness, diurnal variation in mood, and early or late insomnia were able to differentiate the two disorders with almost 90% accuracy, while symptoms such as irritability, retardation and weight loss were common to both and unable to differentiate the two. (RH).
Accession NumberCPA-011115204 A
ClassmarkENR: CT: EA

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