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Centre for Policy on Ageing | |
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| Longitudinal follow-up of depressive symptoms among normal versus cognitively impaired elderly | | Author(s) | Yan-Sheng Li, John S Meyer, John Thornby |
| Journal title | International Journal of Geriatric Psychiatry, vol 16, no 7, July 2001 |
| Pages | pp 718-727 |
| Keywords | Depression ; Symptoms ; Mental health [elderly] ; Mental disorder ; Longitudinal surveys ; United States of America. |
| Annotation | 146 subjects with normal cognition, 19 with mild cognitive impairment (MCI), 42 patients with dementia of the Alzheimer's type (DAT), and 32 with vascular dementia (VAD) were followed for a mean of 3.5 years. With the passage of time, there were trends showing prevalence of depressive symptoms to decrease among DAT and to increase among VAD patients. VAD patients exhibited the highest incidence of new-onset depressive symptoms, followed in incidence by DAT and MCI groups. Depressive symptoms in VAD and MCI patients were more persistent and refractory to antidepressant medications than for DAT patients. Trends suggested that antidepressant treatment might benefit MCI and VAD subjects more than DAT patients. Motivationally related depressive symptoms accounted for major complications of elevated Hamilton Depression Rating Scale (HDRS) scores. Early depressive symptoms in those with MCI may represent a preclinical sign that should be considered as a risk factor for impending DAT or VAD in older people. (RH). |
| Accession Number | CPA-010815206 A |
| Classmark | ENR: CT: D: E: 3J: 7T |
Data © Centre for Policy on Ageing |
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| ...from the Ageinfo database published by Centre for Policy on Ageing. |
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