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Anticipating response to predictive genetic testing for Alzheimer's disease
 — a survey of first-degree relatives
Author(s)J Scott Roberts
Journal titleThe Gerontologist, vol 40, no 1, February 2000
Pagespp 43-52
KeywordsDementia ; Screening ; Attitude ; Children [offspring] ; Siblings ; Social surveys ; United States of America.
Annotation203 siblings and children of patients with Alzheimer's disease (AD) - age range 30-92 and 73% female - were surveyed regarding potential predictive testing options for the disorder. A postal questionnaire posed various hypothetical scenarios and assessed interest in testing, perceptions of pros and cons, and psychological and demographic predictors of test intentions. In 5 of 6 scenarios, most of the participants expressed intentions to pursue testing. The most important reasons for seeking testing were informing later-life decisions and planning future AD care. Predictors of test intentions were male gender, information-seeking style, higher perceived AD threat, and appraisal of test pros versus cons. Situational factors such as available treatment options and certainty of test information also affected responses. Findings of this study may inform AD genetic counselling and health education efforts. (RH).
Accession NumberCPA-010718207 A
ClassmarkEA: 3V: DP: SS: SV: 3F: 7T

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