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Longitudinal and genetic effects in the relationship between pulmonary function and cognitive performance
Author(s)Charles F Emery, Nancy L Pedersen, Magnus Svartengren
Journal titleThe Journals of Gerontology Series B: Psychological Sciences and Social Sciences, vol 53B, no 5, September 1998
Pagespp P311-P317
KeywordsCardiovascular systems ; Mental health [elderly] ; Biological ageing ; Twins ; Longitudinal surveys ; Sweden.
AnnotationPrevious studies have found cognitive deficits in patients with impaired pulmonary function, and recent data from healthy older people suggest an association of pulmonary function with cognitive function. This 6-year longitudinal study evaluated genetic and environmental sources of covariance in the association of pulmonary function with cognitive function of 222 twin pairs (60% women) from the Swedish Adoption/Twin Study of Aging (SATSA), mean age 62.3, age range 40-84. Hierarchical multiple regression analyses, controlling for the effects of age, gender and height were used to predict performance on cognitive tests of fluid and crystallised intelligence from forced expiratory volume in one second (FEV1). Results from bivariate cross-twin correlations indicated that FEV1, predicted performance on tests of fluid intelligence but not crystallised intelligence at the initial assessment and at follow-up. Cross-twin correlation analysis indicated that genetic effects accounted for a greater share of the association of pulmonary function and cognitive performance than environmental effects, but environment also accounted for a substantial share of the covariance. (RH).
Accession NumberCPA-010117205 A
ClassmarkBKK: D: BH: SVR: 3J: 76P

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