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Prevalence and risks of dementia in the Japanese population
 — RERF's Adult Health Study Hiroshima subjects
Author(s)Michiko Yamada, Hideo Sasaki, Yasuyo Mimori
Journal titleJournal of the American Geriatrics Society, vol 47, no 2, February 1999
Pagespp 189-195
KeywordsDementia ; Hazards ; Japan.
Annotation637 men and 1585 women aged 60 and over from the original Adult Health Study (AHS) cohort of atomic bomb survivors and their controls selected from Hiroshima and Nagasaki residents were included in this study. 48 subjects were resident in hospitals and institutions. In addition to biennial medical examinations ongoing since 1958, a screening test for cognitive impairment (CASI) was conducted by trained nurses between September 1992 and September 1996. The prevalence of dementia and its subtypes was assessed in 343 subjects suspected to have dementia and in 272 subjects with high CASI scores who were selected randomly. The prevalence of dementia based on DSM-III/R criteria, using neurological examination, the IQCODE, and CDR, was 7.2%. The prevalence of Alzheimer's disease (AD) was 2% in men and 3.8% in women; and the prevalence of vascular dementia was 2% in men and 1.8% in women. The relationship of risk factors to AD or vascular dementia was investigated: neither type of dementia showed any significant effect of sex or radiation exposure. This study is the first of Japanese dementia rates carried out with a protocol similar enough to that of a US study to allow meaningful comparison. (RH).
Accession NumberCPA-001107001 A
ClassmarkEA: OK7: 7DT

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