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Centre for Policy on Ageing | |
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| Depressive symptoms and risk of Alzheimer's disease in more highly educated older people | | Author(s) | Mirjam I Geerlings, Ben Schmand, Arjan W Braam |
| Journal title | Journal of the American Geriatrics Society, vol 48, no 9, September 2000 |
| Pages | pp 1092-1097 |
| Keywords | Depression ; Dementia ; Educational status [elderly] ; Netherlands. |
| Annotation | In an earlier study, the authors observed that a depressive syndrome was highly predictive of developing Alzheimer's disease (AD) in older people with normal baseline cognition and higher levels of education. This study examines whether specific symptoms of depression can be identified that predict AD among older subjects with higher levels of education. A sample of 3147 Dutch non-demented and with normal cognition aged 65 to 84 from the Amsterdam Study of the Elderly (AMSTEL) were divided into two groups with more than 8 and 8 or less years of education. After average follow-up of 3.2 years, 1911 people were re-evaluated, of who 22 with more than 8 years and 31 with 8 or less years of education had developed AD. For those with more than 8 years of education, depressed mood and subjective bradyphrenia were strongly associated with incident AD. No association between depressive symptoms and AD were observed among those with 8 or less years of education. Both depressive mood and subjective bradyphrenia seem to indicate subclinical AD in older people with higher levels of education. (RH). |
| Accession Number | CPA-001020214 A |
| Classmark | ENR: EA: F:V: 76H |
Data © Centre for Policy on Ageing |
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| ...from the Ageinfo database published by Centre for Policy on Ageing. |
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