| |
Centre for Policy on Ageing | |
 | |
|
The association between low diastolic blood pressure in middle age and cognitive function in old age
— a population-based study | | Author(s) | Lena Kilander, Håkan Nyman, Merike Boberg |
| Journal title | Age and Ageing, vol 29, no 3, May 2000 |
| Pages | pp 243-248 |
| Keywords | Blood pressure ; Middle aged ; Cognitive processes ; Older men ; Correlation ; Sweden. |
| Annotation | Previous longitudinal studies have shown an inverse relation between blood pressure and cognitive function. In this study determining the association between mid-life blood pressure and cognitive function in late life, participants were 502 men aged 69-74 from a population-based cohort in Uppsala, Sweden. Blood pressure had been measured at age 50; performance was examined in 13 psychometric tests about 20 years later. After excluding 39 men with previous stroke, an inverse relation was found between diastolic blood pressure at age 50 and performance 20 years later in the digit span test, the trail-making tests and in verbal fluency. The relationships were significant, independently of age, education and previous occupational level. Men within the lowest category of diastolic blood pressure (equal to or less than 70 mmHg) showed the best results. Baseline blood pressure levels were not linked to performance in tasks on vocabulary, verbal learning and memory or figure copying. Low blood pressure in mid-life indicates a low long-term cerebrovascular risk, and is associated with higher late-life performance in cognitive tests that mainly assess subcortico-frontal cognitive functions. (RH). |
| Accession Number | CPA-000824229 A |
| Classmark | BKL: SE: DA: BC: 49: 76P |
Data © Centre for Policy on Ageing |
|
| ...from the Ageinfo database published by Centre for Policy on Ageing. |
| |
|