Centre for Policy on Ageing



Association of Alzheimer's disease and smoking — the case for sibling controls
Author(s)	Sara M Debanne, Douglas Y Rowland, Tatian M Riedel
Journal title	Journal of the American Geriatrics Society, vol 48, no 7, July 2000
Pages	pp 800-806
Keywords	Dementia ; Tobacco smoking ; Correlation ; Siblings ; United States of America.
Annotation	The association between Alzheimer's disease and smoking remains unclear. For this study, AD cases were identified through the Research Registry of the University Hospitals of the Cleveland / Case Western Reserve University Alzheimer Center. Study subjects were 86 probable AD cases and all of their full siblings, alive or dead, aged 50 and over, a total of 238 subjects. Chi-square analysis tested departure from a random distribution of disease across smokers and non-smokers within families. No significant association was found between smoking and cognitive status. Further, analyses based on the comparison of those with AD with their unaffected siblings also suggest that smoking does not decrease the risk of AD. (RH).
Accession Number	CPA-000824224 A
Classmark	EA: ETT: 49: SV: 7T
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...from the Ageinfo database published by Centre for Policy on Ageing.